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詳細資料ISBN:9780262025065 叢書系列:化學及化學工程 規格:普通級 內容簡介AN UNPRECEDENTED WEALTH OF DATA IS BEING GENERATED BY GENOME SEQUENCING PROJECTS AND OTHER EXPERIMENTAL EFFORTS TO DETERMINE THE STRUCTURE AND FUNCTION OF BIOLOGICAL MOLECULES. THE DEMANDS AND OPPORTUNITIES FOR INTERPRETING THESE DATA ARE EXPANDING RAPIDLY. BIOINFORMATICS IS THE DEVELOPMENT AND APPLICATION OF COMPUTER METHODS FOR MANAGEMENT, ANALYSIS, INTERPRETATION, AND PREDICTION, AS WELL AS FOR THE DESIGN OF EXPERIMENTS. MACHINE LEARNING APPROACHES (E.G., NEURAL NETWORKS, HIDDEN MARKOV MODELS, AND BELIEF NETWORKS) ARE IDEALLY SUITED FOR AREAS WHERE THERE IS A LOT OF DATA BUT LITTLE THEORY, WHICH IS THE SITUATION IN MOLECULAR BIOLOGY. THE GOAL IN MACHINE LEARNING IS TO EXTRACT USEFUL INFORMATION FROM A BODY OF DATA BY BUILDING GOOD PROBABILISTIC MODELS--AND TO AUTOMATE THE PROCESS AS MUCH AS POSSIBLE.IN THIS BOOK PIERRE BALDI AND SøREN BRUNAK PRESENT THE KEY MACHINE LEARNING APPROACHES AND APPLY THEM TO THE COMPUTATIONAL PROBLEMS ENCOUNTERED IN THE ANALYSIS OF BIOLOGICAL DATA. THE BOOK IS AIMED BOTH AT BIOLOGISTS AND BIOCHEMISTS WHO NEED TO UNDERSTAND NEW DATA-DRIVEN ALGORITHMS AND AT THOSE WITH A PRIMARY BACKGROUND IN PHYSICS, MATHEMATICS, STATISTICS, OR COMPUTER SCIENCE WHO NEED TO KNOW MORE ABOUT APPLICATIONS IN MOLECULAR BIOLOGY.THIS NEW SECOND EDITION CONTAINS EXPANDED COVERAGE OF PROBABILISTIC GRAPHICAL MODELS AND OF THE APPLICATIONS OF NEURAL NETWORKS, AS WELL AS A NEW CHAPTER ON MICROARRAYS AND GENE EXPRESSION. THE ENTIRE TEXT HAS BEEN EXTENSIVELY REVISED. |
搜尋參考資料: 1. biochem218.stanford.edu/01Genomics&Bioinformatics.pdf Genomics and Bioinformatics Doug Brutlag Professor Emeritus Biochemistry & Medicine (by courtesy) Computational Molecular Biology Biochem 218 – BioMedical ... www.academia.edu/1537232/Bioinformatics_Tools_and_Applications Academia.edu is a platform for academics to share research papers. www.sbioinformatics.com/design_thesis/Soda_ash/Soda-2520ash... or weak soda ash liquors to dissolve the soda ash and soluble impurities, such as sodium chloride and sodium sulphate. Insoluble material, consisting of shale, clay ... www.ebi.ac.uk/interpro/potm/2005_10/Page1.htm Haemoglobin By Jennifer McDowall . Link to the structural features of haemoglobin When we breathe in oxygen, the red blood cells transport it around ... jura.wi.mit.edu/bio/education/hot_topics/pdf/matlab.pdf Statistical Analysis in MATLAB Hot Topic – 18 Jan 2006 Sanjeev Pillai BARC Bioinformatics 2,e |
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